Design of Glycoconjugate Vaccines against Invasive African Salmonella enterica Serovar Typhimurium

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Design of glycoconjugate vaccines against invasive African Salmonella enterica serovar Typhimurium.

Nontyphoidal salmonellae, particularly Salmonella enterica serovar Typhimurium, are a major cause of invasive disease in Africa, affecting mainly young children and HIV-infected individuals. Glycoconjugate vaccines provide a safe and reliable strategy against invasive polysaccharide-encapsulated pathogens, and lipopolysaccharide (LPS) is a target of protective immune responses. With the aim of ...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 2014

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.03079-14